Gene number expansion and contraction in vertebrate genomes with respect to invertebrate genomes
نویسندگان
چکیده
منابع مشابه
Gene number expansion and contraction in vertebrate genomes with respect to invertebrate genomes.
Where did vertebrate genes come from? Here we address this question by analyzing eight completely sequenced land vertebrate genomes and six completely sequenced invertebrate genomes. Approximately 70% of the vertebrate genes can be found in the six invertebrate genomes with the standard homology search criteria (denoted as V.MCL), another approximately 6% can be found with relaxed search criter...
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The mouse Surfeit locus contains six sequence-unrelated genes (Surf-1 to -6) arranged in the tightest gene cluster so far described for mammals. The organization and juxtaposition of five of the Surfeit genes (Surf-1 to -5) are conserved between mammals and birds, and this may reflect a functional or regulatory requirement for the gene clustering. We have undertaken an evolutionary study to det...
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Overlapping genes in mammalian genomes are unexpected phenomena even though hundreds of pairs of protein coding overlapping genes have been reported so far. Overlapping genes can be divided into different categories based on direction of transcription as well as on sequence segments being shared between overlapping coding regions. The biologic functions of natural antisense transcripts, their i...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2008
ISSN: 1088-9051
DOI: 10.1101/gr.7046608